Altered synaptic connectivity in an in vitro human model of STXBP1 encephalopathy

Early infantile developmental and epileptic encephalopathies are devastating conditions, generally of genetic origin, but the pathological mechanisms often remain obscure. A major obstacle in this field of research is the difficulty of studying cortical brain development in humans, at the relevant t...

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Detalles Bibliográficos
Autores principales: McLeod, Faye, Dimtsi, Anna, Marshall, Amy C, Lewis-Smith, David, Thomas, Rhys, Clowry, Gavin J, Trevelyan, Andrew J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9976961/
https://www.ncbi.nlm.nih.gov/pubmed/36315647
http://dx.doi.org/10.1093/brain/awac396

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9976961/
https://www.ncbi.nlm.nih.gov/pubmed/36315647
http://dx.doi.org/10.1093/brain/awac396

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