Cargando…
NS5A domain I antagonises PKR to facilitate the assembly of infectious hepatitis C virus particles
Hepatitis C virus NS5A is a multifunctional phosphoprotein comprised of three domains (DI, DII and DIII). DI and DII have been shown to function in genome replication, whereas DIII has a role in virus assembly. We previously demonstrated that DI in genotype 2a (JFH1) also plays a role in virus assem...
| Autores principales: | , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2023
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9977016/ https://www.ncbi.nlm.nih.gov/pubmed/36795772 http://dx.doi.org/10.1371/journal.ppat.1010812 |