Parkinsonian phenotypes induced by Synphilin-1 expression are differentially contributed by serotonergic and dopaminergic circuits and suppressed by nicotine treatment

Synphilin-1 is a protein encoded by the human SNCAIP gene whose function has yet to be fully understood. However, it has been linked to familial Parkinson’s disease (PD). Synphilin-1 is a major component of the Lewy bodies found in neurons in the substantia nigra pars compacta of PD patients. Synphi...

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Detalles Bibliográficos
Autores principales: Carvajal-Oliveros, Angel, Dominguez-Baleón, Carmen, Sánchez-Díaz, Iván, Zambrano-Tipan, Diego, Hernández-Vargas, René, Campusano, Jorge M., Narváez-Padilla, Verónica, Reynaud, Enrique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9977059/
https://www.ncbi.nlm.nih.gov/pubmed/36857384
http://dx.doi.org/10.1371/journal.pone.0282348

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9977059/
https://www.ncbi.nlm.nih.gov/pubmed/36857384
http://dx.doi.org/10.1371/journal.pone.0282348

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