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Leptomeningeal Carcinomatosis and Palliative Care: A Case Report

Leptomeningeal carcinomatosis (LC) is a rare but serious complication of cancer in which cancer cells spread to the leptomeninges, the membranes that surround the brain and spinal cord. The diagnosis and treatment of LC can be challenging due to the non-specific symptoms and the difficulty of access...

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Autores principales: Shanbhag, Nandan M, Elbakheit, Mehad M, Javed, Muhammad Z, Elomami, Abdulghani, Samad, Afroz, Abdulrahman, Bahaa E, Ibrahim, Huzaifa G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9977077/
https://www.ncbi.nlm.nih.gov/pubmed/36874311
http://dx.doi.org/10.7759/cureus.35615
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author Shanbhag, Nandan M
Elbakheit, Mehad M
Javed, Muhammad Z
Elomami, Abdulghani
Samad, Afroz
Abdulrahman, Bahaa E
Ibrahim, Huzaifa G
author_facet Shanbhag, Nandan M
Elbakheit, Mehad M
Javed, Muhammad Z
Elomami, Abdulghani
Samad, Afroz
Abdulrahman, Bahaa E
Ibrahim, Huzaifa G
author_sort Shanbhag, Nandan M
collection PubMed
description Leptomeningeal carcinomatosis (LC) is a rare but serious complication of cancer in which cancer cells spread to the leptomeninges, the membranes that surround the brain and spinal cord. The diagnosis and treatment of LC can be challenging due to the non-specific symptoms and the difficulty of accessing the leptomeninges for a biopsy. In this case report, we describe a patient with advanced breast cancer who was diagnosed with LC and underwent treatment with chemotherapy. Despite aggressive treatment, the patient's condition worsened over time, and she was referred to palliative care, where adequate symptom control was achieved, and she was discharged to her home country as per her wish. Our case highlights the difficulties associated with the diagnosis and treatment of LC and the need for continued research to improve outcomes for patients with this condition. It specifically highlights the approach a palliative care team can take for this condition.
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spelling pubmed-99770772023-03-02 Leptomeningeal Carcinomatosis and Palliative Care: A Case Report Shanbhag, Nandan M Elbakheit, Mehad M Javed, Muhammad Z Elomami, Abdulghani Samad, Afroz Abdulrahman, Bahaa E Ibrahim, Huzaifa G Cureus Pain Management Leptomeningeal carcinomatosis (LC) is a rare but serious complication of cancer in which cancer cells spread to the leptomeninges, the membranes that surround the brain and spinal cord. The diagnosis and treatment of LC can be challenging due to the non-specific symptoms and the difficulty of accessing the leptomeninges for a biopsy. In this case report, we describe a patient with advanced breast cancer who was diagnosed with LC and underwent treatment with chemotherapy. Despite aggressive treatment, the patient's condition worsened over time, and she was referred to palliative care, where adequate symptom control was achieved, and she was discharged to her home country as per her wish. Our case highlights the difficulties associated with the diagnosis and treatment of LC and the need for continued research to improve outcomes for patients with this condition. It specifically highlights the approach a palliative care team can take for this condition. Cureus 2023-02-28 /pmc/articles/PMC9977077/ /pubmed/36874311 http://dx.doi.org/10.7759/cureus.35615 Text en Copyright © 2023, Shanbhag et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Pain Management
Shanbhag, Nandan M
Elbakheit, Mehad M
Javed, Muhammad Z
Elomami, Abdulghani
Samad, Afroz
Abdulrahman, Bahaa E
Ibrahim, Huzaifa G
Leptomeningeal Carcinomatosis and Palliative Care: A Case Report
title Leptomeningeal Carcinomatosis and Palliative Care: A Case Report
title_full Leptomeningeal Carcinomatosis and Palliative Care: A Case Report
title_fullStr Leptomeningeal Carcinomatosis and Palliative Care: A Case Report
title_full_unstemmed Leptomeningeal Carcinomatosis and Palliative Care: A Case Report
title_short Leptomeningeal Carcinomatosis and Palliative Care: A Case Report
title_sort leptomeningeal carcinomatosis and palliative care: a case report
topic Pain Management
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9977077/
https://www.ncbi.nlm.nih.gov/pubmed/36874311
http://dx.doi.org/10.7759/cureus.35615
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