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Childhood cancer and hematological disorders negatively affect spermatogonial quantity at diagnosis: a retrospective study of a male fertility preservation cohort
STUDY QUESTION: What is the impact of cancer or hematological disorders on germ cells in pediatric male patients? SUMMARY ANSWER: Spermatogonial quantity is reduced in testes of prepubertal boys diagnosed with cancer or severe hematological disorder compared to healthy controls and this reduction is...
Autores principales: | Masliukaite, Ieva, Ntemou, Elissavet, Feijen, Elizabeth A M, van de Wetering, Marianne, Meissner, Andreas, Soufan, Alexandre T, Repping, Sjoerd, Kremer, Leontien M C, Jahnukainen, Kirsi, Goossens, Ellen, van Pelt, Ans M M |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9977127/ https://www.ncbi.nlm.nih.gov/pubmed/36708005 http://dx.doi.org/10.1093/humrep/dead004 |
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