Active enhancers strengthen insulation by RNA-mediated CTCF binding at chromatin domain boundaries

Vertebrate genomes are partitioned into chromatin domains or topologically associating domains (TADs), which are typically bound by head-to-head pairs of CTCF binding sites. Transcription at domain boundaries correlates with better insulation; however, it is not known whether the boundary transcript...

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Detalles Bibliográficos
Autores principales: Islam, Zubairul, Saravanan, Bharath, Walavalkar, Kaivalya, Farooq, Umer, Singh, Anurag Kumar, Radhakrishnan, Sabarinathan, Thakur, Jitendra, Pandit, Awadhesh, Henikoff, Steven, Notani, Dimple
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9977152/
https://www.ncbi.nlm.nih.gov/pubmed/36650052
http://dx.doi.org/10.1101/gr.276643.122

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