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ATM-SPARK: A GFP phase separation–based activity reporter of ATM

The kinase ataxia telangiectasia mutated (ATM) plays a key role in the DNA damage response (DDR). It is thus essential to visualize spatiotemporal dynamics of ATM activity during DDR. Here, we designed a robust ATM activity reporter based on phosphorylation-inducible green fluorescent protein phase...

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Detalles Bibliográficos
Autores principales: Li, Xiaoquan, Chung, Chan-I, Yang, JunJiao, Chaudhuri, Sibapriya, Munster, Pamela N., Shu, Xiaokun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9977181/
https://www.ncbi.nlm.nih.gov/pubmed/36857446
http://dx.doi.org/10.1126/sciadv.ade3760