Distinct roles for canonical and variant histone H3 lysine-36 in Polycomb silencing

Polycomb complexes regulate cell type–specific gene expression programs through heritable silencing of target genes. Trimethylation of histone H3 lysine 27 (H3K27me3) is essential for this process. Perturbation of H3K36 is thought to interfere with H3K27me3. We show that mutants of Drosophila replic...

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Detalles Bibliográficos
Autores principales: Salzler, Harmony R., Vandadi, Vasudha, McMichael, Benjamin D., Brown, John C., Boerma, Sally A., Leatham-Jensen, Mary P., Adams, Kirsten M., Meers, Michael P., Simon, Jeremy M., Duronio, Robert J., McKay, Daniel J., Matera, A. Gregory
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9977188/
https://www.ncbi.nlm.nih.gov/pubmed/36857457
http://dx.doi.org/10.1126/sciadv.adf2451

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