Recurrent Brain Metastasis Versus Radiation-Induced Necrosis: A Case Report and Literature Review

Radiotherapy is the cornerstone of brain metastasis management. With the advancement of therapies, patients are living longer, exposing them to the long-term effects of radiotherapy. Using concurrent or sequential chemotherapy, targeted agents, and immune checkpoint inhibitors may increase the incid...

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Detalles Bibliográficos
Autores principales: Sweidan, Hisham, Jarrah, Abdullah, Weingarten, Aron, Zhu, Feng, AlQasem, Sarah, Manasrah, Nouraldeen, Chaudhary, Ahmed Jamal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Internal Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9977201/
https://www.ncbi.nlm.nih.gov/pubmed/36874691
http://dx.doi.org/10.7759/cureus.34400
Descripción
Sumario:Radiotherapy is the cornerstone of brain metastasis management. With the advancement of therapies, patients are living longer, exposing them to the long-term effects of radiotherapy. Using concurrent or sequential chemotherapy, targeted agents, and immune checkpoint inhibitors may increase the incidence and severity of radiation-induced toxicity. Recurrent metastasis and radiation necrosis (RN) appear indistinguishable on neuroimaging, making it a diagnostic dilemma for clinicians. Here, we present a case of RN in a 65-year-old male patient who previously had brain metastasis (BM) from primary lung cancer, misdiagnosed initially as recurrent BM.

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