Recurrent Brain Metastasis Versus Radiation-Induced Necrosis: A Case Report and Literature Review

Radiotherapy is the cornerstone of brain metastasis management. With the advancement of therapies, patients are living longer, exposing them to the long-term effects of radiotherapy. Using concurrent or sequential chemotherapy, targeted agents, and immune checkpoint inhibitors may increase the incid...

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Autores principales: Sweidan, Hisham, Jarrah, Abdullah, Weingarten, Aron, Zhu, Feng, AlQasem, Sarah, Manasrah, Nouraldeen, Chaudhary, Ahmed Jamal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Internal Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9977201/
https://www.ncbi.nlm.nih.gov/pubmed/36874691
http://dx.doi.org/10.7759/cureus.34400
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author Sweidan, Hisham
Jarrah, Abdullah
Weingarten, Aron
Zhu, Feng
AlQasem, Sarah
Manasrah, Nouraldeen
Chaudhary, Ahmed Jamal
author_facet Sweidan, Hisham
Jarrah, Abdullah
Weingarten, Aron
Zhu, Feng
AlQasem, Sarah
Manasrah, Nouraldeen
Chaudhary, Ahmed Jamal
author_sort Sweidan, Hisham
collection PubMed
description Radiotherapy is the cornerstone of brain metastasis management. With the advancement of therapies, patients are living longer, exposing them to the long-term effects of radiotherapy. Using concurrent or sequential chemotherapy, targeted agents, and immune checkpoint inhibitors may increase the incidence and severity of radiation-induced toxicity. Recurrent metastasis and radiation necrosis (RN) appear indistinguishable on neuroimaging, making it a diagnostic dilemma for clinicians. Here, we present a case of RN in a 65-year-old male patient who previously had brain metastasis (BM) from primary lung cancer, misdiagnosed initially as recurrent BM.
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spelling pubmed-99772012023-03-02 Recurrent Brain Metastasis Versus Radiation-Induced Necrosis: A Case Report and Literature Review Sweidan, Hisham Jarrah, Abdullah Weingarten, Aron Zhu, Feng AlQasem, Sarah Manasrah, Nouraldeen Chaudhary, Ahmed Jamal Cureus Internal Medicine Radiotherapy is the cornerstone of brain metastasis management. With the advancement of therapies, patients are living longer, exposing them to the long-term effects of radiotherapy. Using concurrent or sequential chemotherapy, targeted agents, and immune checkpoint inhibitors may increase the incidence and severity of radiation-induced toxicity. Recurrent metastasis and radiation necrosis (RN) appear indistinguishable on neuroimaging, making it a diagnostic dilemma for clinicians. Here, we present a case of RN in a 65-year-old male patient who previously had brain metastasis (BM) from primary lung cancer, misdiagnosed initially as recurrent BM. Cureus 2023-01-30 /pmc/articles/PMC9977201/ /pubmed/36874691 http://dx.doi.org/10.7759/cureus.34400 Text en Copyright © 2023, Sweidan et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Internal Medicine
Sweidan, Hisham
Jarrah, Abdullah
Weingarten, Aron
Zhu, Feng
AlQasem, Sarah
Manasrah, Nouraldeen
Chaudhary, Ahmed Jamal
Recurrent Brain Metastasis Versus Radiation-Induced Necrosis: A Case Report and Literature Review
title Recurrent Brain Metastasis Versus Radiation-Induced Necrosis: A Case Report and Literature Review
title_full Recurrent Brain Metastasis Versus Radiation-Induced Necrosis: A Case Report and Literature Review
title_fullStr Recurrent Brain Metastasis Versus Radiation-Induced Necrosis: A Case Report and Literature Review
title_full_unstemmed Recurrent Brain Metastasis Versus Radiation-Induced Necrosis: A Case Report and Literature Review
title_short Recurrent Brain Metastasis Versus Radiation-Induced Necrosis: A Case Report and Literature Review
title_sort recurrent brain metastasis versus radiation-induced necrosis: a case report and literature review
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9977201/
https://www.ncbi.nlm.nih.gov/pubmed/36874691
http://dx.doi.org/10.7759/cureus.34400
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