Deacetylation of Septin4 by SIRT2 (Silent Mating Type Information Regulation 2 Homolog-2) Mitigates Damaging of Hypertensive Nephropathy

Hypertension can lead to podocyte damage and subsequent apoptosis, eventually resulting in glomerulosclerosis. Although alleviating podocyte apoptosis has clinical significance for the treatment of hypertensive nephropathy, an effective therapeutic target has not yet been identified. The function of...

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Detalles Bibliográficos
Autores principales: Zhang, Ying, Zhang, Naijin, Zou, Yuanming, Song, Chunyu, Cao, Kexin, Wu, Boquan, You, Shilong, Lu, Saien, Wang, Dong, Xu, Jiaqi, Huang, Xinyue, Zhang, Pengyu, Fan, Zihao, Liu, Jingwei, Cheng, Zhongyi, Zhang, Zhe, Kong, Chuize, Cao, Liu, Sun, Yingxian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9977266/
https://www.ncbi.nlm.nih.gov/pubmed/36786216
http://dx.doi.org/10.1161/CIRCRESAHA.122.321591

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