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Chloride ions evoke taste sensations by binding to the extracellular ligand-binding domain of sweet/umami taste receptors
Salt taste sensation is multifaceted: NaCl at low or high concentrations is preferably or aversively perceived through distinct pathways. Cl(−) is thought to participate in taste sensation through an unknown mechanism. Here, we describe Cl(−) ion binding and the response of taste receptor type 1 (T1...
Autores principales: | Atsumi, Nanako, Yasumatsu, Keiko, Takashina, Yuriko, Ito, Chiaki, Yasui, Norihisa, Margolskee, Robert F, Yamashita, Atsuko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9977269/ https://www.ncbi.nlm.nih.gov/pubmed/36852482 http://dx.doi.org/10.7554/eLife.84291 |
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