MDA5-dependent responses contribute to autoimmune diabetes progression and hindrance

Type 1 diabetes (T1D) is an autoimmune disease resulting in pancreatic β cell destruction. Coxsackievirus B3 (CVB3) infection and melanoma differentiation-associated protein 5–dependent (MDA5-dependent) antiviral responses are linked with T1D development. Mutations within IFIH1, coding for MDA5, are...

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Detalles Bibliográficos
Autores principales: Blum, Samuel I., Taylor, Jared P., Barra, Jessie M., Burg, Ashley R., Shang, Qiao, Qiu, Shihong, Shechter, Oren, Hayes, Aleah R., Green, Todd J., Geurts, Aron M., Chen, Yi-Guang, Tse, Hubert M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9977297/
https://www.ncbi.nlm.nih.gov/pubmed/36512407
http://dx.doi.org/10.1172/jci.insight.157929

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9977297/
https://www.ncbi.nlm.nih.gov/pubmed/36512407
http://dx.doi.org/10.1172/jci.insight.157929

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