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Medium-chain fatty acids suppress lipotoxicity-induced hepatic fibrosis via the immunomodulating receptor GPR84

Medium-chain triglycerides (MCTs), which consist of medium-chain fatty acids (MCFAs), are unique forms of dietary fat with various health benefits. G protein–coupled 84 (GPR84) acts as a receptor for MCFAs (especially C10:0 and C12:0); however, GPR84 is still considered an orphan receptor, and the n...

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Detalles Bibliográficos
Autores principales: Ohue-Kitano, Ryuji, Nonaka, Hazuki, Nishida, Akari, Masujima, Yuki, Takahashi, Daisuke, Ikeda, Takako, Uwamizu, Akiharu, Tanaka, Miyako, Kohjima, Motoyuki, Igarashi, Miki, Katoh, Hironori, Tanaka, Tomohiro, Inoue, Asuka, Suganami, Takayoshi, Hase, Koji, Ogawa, Yoshihiro, Aoki, Junken, Kimura, Ikuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9977302/
https://www.ncbi.nlm.nih.gov/pubmed/36480287
http://dx.doi.org/10.1172/jci.insight.165469