Spatial transcriptomic characterization of COVID-19 pneumonitis identifies immune circuits related to tissue injury

Severe lung damage resulting from COVID-19 involves complex interactions between diverse populations of immune and stromal cells. In this study, we used a spatial transcriptomics approach to delineate the cells, pathways, and genes present across the spectrum of histopathological damage in COVID-19–...

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Detalles Bibliográficos
Autores principales: Cross, Amy R., de Andrea, Carlos E., Villalba-Esparza, María, Landecho, Manuel F., Cerundolo, Lucia, Weeratunga, Praveen, Etherington, Rachel E., Denney, Laura, Ogg, Graham, Ho, Ling-Pei, Roberts, Ian S.D., Hester, Joanna, Klenerman, Paul, Melero, Ignacio, Sansom, Stephen N., Issa, Fadi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9977306/
https://www.ncbi.nlm.nih.gov/pubmed/36472908
http://dx.doi.org/10.1172/jci.insight.157837

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