Next-generation membrane-active glycopeptide antibiotics that also inhibit bacterial cell division

Resistance to vancomycin, a life-saving drug against Gram-positive bacterial infections necessitates developing alternative therapeutics. Herein, we report vancomycin derivatives that assimilate mechanisms beyond d-Ala–d-Ala binding. The role of hydrophobicity towards the structure and function of t...

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Detalles Bibliográficos
Autores principales: Sarkar, Paramita, De, Kathakali, Modi, Malvika, Dhanda, Geetika, Priyadarshini, Richa, Bandow, Julia E., Haldar, Jayanta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9977398/
https://www.ncbi.nlm.nih.gov/pubmed/36873852
http://dx.doi.org/10.1039/d2sc05600c

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9977398/
https://www.ncbi.nlm.nih.gov/pubmed/36873852
http://dx.doi.org/10.1039/d2sc05600c

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