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Next-generation membrane-active glycopeptide antibiotics that also inhibit bacterial cell division
Resistance to vancomycin, a life-saving drug against Gram-positive bacterial infections necessitates developing alternative therapeutics. Herein, we report vancomycin derivatives that assimilate mechanisms beyond d-Ala–d-Ala binding. The role of hydrophobicity towards the structure and function of t...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Royal Society of Chemistry
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9977398/ https://www.ncbi.nlm.nih.gov/pubmed/36873852 http://dx.doi.org/10.1039/d2sc05600c |