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Mitochondrial and NAD(+) metabolism predict recovery from acute kidney injury in a diverse mouse population

Acute kidney failure and chronic kidney disease are global health issues steadily rising in incidence and prevalence. Animal models on a single genetic background have so far failed to recapitulate the clinical presentation of human nephropathies. Here, we used a simple model of folic acid–induced k...

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Detalles Bibliográficos
Autores principales: Morel, Jean-David, Sleiman, Maroun Bou, Li, Terytty Yang, von Alvensleben, Giacomo, Bachmann, Alexis M., Hofer, Dina, Broeckx, Ellen, Ma, Jing Ying, Carreira, Vinicius, Chen, Tao, Azhar, Nabil, Gonzalez-Villalobos, Romer A., Breyer, Matthew, Reilly, Dermot, Mullican, Shannon, Auwerx, Johan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9977436/
https://www.ncbi.nlm.nih.gov/pubmed/36752209
http://dx.doi.org/10.1172/jci.insight.164626