Slow progression of pediatric HIV associates with early CD8(+) T cell PD-1 expression and a stem-like phenotype

HIV nonprogression despite persistent viremia is rare among adults who are naive to antiretroviral therapy (ART) but relatively common among ART-naive children. Previous studies indicate that ART-naive pediatric slow progressors (PSPs) adopt immune evasion strategies similar to those described in na...

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Detalles Bibliográficos
Autores principales: Vieira, Vinicius, Lim, Nicholas, Singh, Alveera, Leitman, Ellen, Dsouza, Reena, Adland, Emily, Muenchhoff, Maximilian, Roider, Julia, Marin Lopez, Miguel, Carabelli, Julieta, Giandhari, Jennifer, Groll, Andreas, Jooste, Pieter, Prado, Julia G., Thobakgale, Christina, Dong, Krista, Kiepiela, Photini, Prendergast, Andrew J., Tudor-Williams, Gareth, Frater, John, Walker, Bruce D., Ndung’u, Thumbi, Ramsuran, Veron, Leslie, Alasdair, Kløverpris, Henrik N., Goulder, Philip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9977437/
https://www.ncbi.nlm.nih.gov/pubmed/36602861
http://dx.doi.org/10.1172/jci.insight.156049

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9977437/
https://www.ncbi.nlm.nih.gov/pubmed/36602861
http://dx.doi.org/10.1172/jci.insight.156049

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