In Humanized Sickle Cell Mice, Imatinib Protects Against Sickle Cell–Related Injury

Drug repurposing is a valuable strategy for rare diseases. Sickle cell disease (SCD) is a rare hereditary hemolytic anemia accompanied by acute and chronic painful episodes, most often in the context of vaso-occlusive crisis (VOC). Although progress in the knowledge of pathophysiology of SCD have al...

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Detalles Bibliográficos
Autores principales: Federti, Enrica, Matte, Alessandro, Recchiuti, Antonio, Garello, Francesca, Ghigo, Alessandra, El Nemer, Wassim, Terreno, Enzo, Amoresano, Angela, Mattoscio, Domenico, Turrini, Franco, Lebouef, Christophe, Janin, Anne, Pantaleo, Antonella, Russo, Roberta, Marin, Mickael, Iatcencko, Iana, Riccardi, Veronica, Siciliano, Angela, Iolascon, Achille, Brugnara, Carlo, De Franceschi, Lucia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9977487/
https://www.ncbi.nlm.nih.gov/pubmed/36874380
http://dx.doi.org/10.1097/HS9.0000000000000848

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