Targeting activin receptor–like kinase 7 ameliorates adiposity and associated metabolic disorders

Activin receptor-like kinase 7 (ALK7) is a type I receptor in the TGF-β superfamily preferentially expressed in adipose tissue and associated with lipid metabolism. Inactivation of ALK7 signaling in mice results in increased lipolysis and resistance to both genetic and diet-induced obesity. Human ge...

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Detalles Bibliográficos
Autores principales: Zhao, Min, Okunishi, Katsuhide, Bu, Yun, Kikuchi, Osamu, Wang, Hao, Kitamura, Tadahiro, Izumi, Tetsuro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9977491/
https://www.ncbi.nlm.nih.gov/pubmed/36626233
http://dx.doi.org/10.1172/jci.insight.161229

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9977491/
https://www.ncbi.nlm.nih.gov/pubmed/36626233
http://dx.doi.org/10.1172/jci.insight.161229

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