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A20 and the noncanonical NF-κB pathway are key regulators of neutrophil recruitment during fetal ontogeny

Newborns are at high risk of developing neonatal sepsis, particularly if born prematurely. This has been linked to divergent requirements the immune system has to fulfill during intrauterine compared with extrauterine life. By transcriptomic analysis of fetal and adult neutrophils, we shed new light...

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Detalles Bibliográficos
Autores principales: Rohwedder, Ina, Wackerbarth, Lou Martha, Heinig, Kristina, Ballweg, Annamaria, Altstätter, Johannes, Ripphahn, Myriam, Nussbaum, Claudia, Salvermoser, Melanie, Bierschenk, Susanne, Straub, Tobias, Gunzer, Matthias, Schmidt-Supprian, Marc, Kolben, Thomas, Schulz, Christian, Ma, Averil, Walzog, Barbara, Heinig, Matthias, Sperandio, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9977499/
https://www.ncbi.nlm.nih.gov/pubmed/36633909
http://dx.doi.org/10.1172/jci.insight.155968