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Type I IFNs link skin-associated dysbiotic commensal bacteria to pathogenic inflammation and angiogenesis in rosacea

Rosacea is a common chronic inflammatory skin disease with a fluctuating course of excessive inflammation and apparent neovascularization. Microbial dysbiosis with a high density of Bacillus oleronius and increased activity of kallikrein 5, which cleaves cathelicidin antimicrobial peptide, are key p...

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Detalles Bibliográficos
Autores principales: Mylonas, Alessio, Hawerkamp, Heike C., Wang, Yichen, Chen, Jiaqi, Messina, Francesco, Demaria, Olivier, Meller, Stephan, Homey, Bernhard, Di Domizio, Jeremy, Mazzolai, Lucia, Hovnanian, Alain, Gilliet, Michel, Conrad, Curdin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9977509/
https://www.ncbi.nlm.nih.gov/pubmed/36633910
http://dx.doi.org/10.1172/jci.insight.151846