Cargando…
Type I IFNs link skin-associated dysbiotic commensal bacteria to pathogenic inflammation and angiogenesis in rosacea
Rosacea is a common chronic inflammatory skin disease with a fluctuating course of excessive inflammation and apparent neovascularization. Microbial dysbiosis with a high density of Bacillus oleronius and increased activity of kallikrein 5, which cleaves cathelicidin antimicrobial peptide, are key p...
Autores principales: | Mylonas, Alessio, Hawerkamp, Heike C., Wang, Yichen, Chen, Jiaqi, Messina, Francesco, Demaria, Olivier, Meller, Stephan, Homey, Bernhard, Di Domizio, Jeremy, Mazzolai, Lucia, Hovnanian, Alain, Gilliet, Michel, Conrad, Curdin |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Clinical Investigation
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9977509/ https://www.ncbi.nlm.nih.gov/pubmed/36633910 http://dx.doi.org/10.1172/jci.insight.151846 |
Ejemplares similares
-
TNF blockade induces a dysregulated type I interferon response without autoimmunity in paradoxical psoriasis
por: Conrad, Curdin, et al.
Publicado: (2018) -
Interleukin-26 activates macrophages and facilitates killing of Mycobacterium tuberculosis
por: Hawerkamp, Heike C., et al.
Publicado: (2020) -
Plasmacytoid dendritic cells and regulatory T cells in the tumor microenvironment: A dangerous liaison
por: Conrad, Curdin, et al.
Publicado: (2013) -
Plasmacytoid dendritic cells sense skin injury and promote wound healing through type I interferons
por: Gregorio, Josh, et al.
Publicado: (2010) -
Tofacitinib downregulates antiviral immune defence in keratinocytes and reduces T cell activation
por: Hawerkamp, Heike C., et al.
Publicado: (2021)