The Senolytic Drug Fisetin Attenuates Bone Degeneration in the Zmpste24(−/−) Progeria Mouse Model

Aging leads to several geriatric conditions including osteoporosis (OP) and associated frailty syndrome. Treatments for these conditions are limited and none target fundamental drivers of pathology, and thus identifying strategies to delay progressive loss of tissue homeostasis and functional reserv...

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Detalles Bibliográficos
Autores principales: Hambright, William S., Mu, Xiaodong, Gao, Xueqin, Guo, Ping, Kawakami, Yohei, Mitchell, John, Mullen, Michael, Nelson, Anna-Laura, Bahney, Chelsea, Nishimura, Haruki, Hellwinkel, Justin, Eck, Andrew, Huard, Johnny
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9977556/
https://www.ncbi.nlm.nih.gov/pubmed/36875869
http://dx.doi.org/10.1155/2023/5572754

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9977556/
https://www.ncbi.nlm.nih.gov/pubmed/36875869
http://dx.doi.org/10.1155/2023/5572754

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