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The Senolytic Drug Fisetin Attenuates Bone Degeneration in the Zmpste24(−/−) Progeria Mouse Model
Aging leads to several geriatric conditions including osteoporosis (OP) and associated frailty syndrome. Treatments for these conditions are limited and none target fundamental drivers of pathology, and thus identifying strategies to delay progressive loss of tissue homeostasis and functional reserv...
Autores principales: | Hambright, William S., Mu, Xiaodong, Gao, Xueqin, Guo, Ping, Kawakami, Yohei, Mitchell, John, Mullen, Michael, Nelson, Anna-Laura, Bahney, Chelsea, Nishimura, Haruki, Hellwinkel, Justin, Eck, Andrew, Huard, Johnny |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9977556/ https://www.ncbi.nlm.nih.gov/pubmed/36875869 http://dx.doi.org/10.1155/2023/5572754 |
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