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Microbiota-derived 3-IAA influences chemotherapy efficacy in pancreatic cancer
Pancreatic ductal adenocarcinoma (PDAC) is expected to be the second most deadly cancer by 2040, owing to the high incidence of metastatic disease and limited responses to treatment(1,2). Less than half of all patients respond to the primary treatment for PDAC, chemotherapy(3,4), and genetic alterat...
Autores principales: | Tintelnot, Joseph, Xu, Yang, Lesker, Till R., Schönlein, Martin, Konczalla, Leonie, Giannou, Anastasios D., Pelczar, Penelope, Kylies, Dominik, Puelles, Victor G., Bielecka, Agata A., Peschka, Manuela, Cortesi, Filippo, Riecken, Kristoffer, Jung, Maximilian, Amend, Lena, Bröring, Tobias S., Trajkovic-Arsic, Marija, Siveke, Jens T., Renné, Thomas, Zhang, Danmei, Boeck, Stefan, Strowig, Till, Uzunoglu, Faik G., Güngör, Cenap, Stein, Alexander, Izbicki, Jakob R., Bokemeyer, Carsten, Sinn, Marianne, Kimmelman, Alec C., Huber, Samuel, Gagliani, Nicola |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9977685/ https://www.ncbi.nlm.nih.gov/pubmed/36813961 http://dx.doi.org/10.1038/s41586-023-05728-y |
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