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Repurposing FDA-approved drugs as FXR agonists: a structure based in silico pharmacological study

Farnesoid X receptor (FXR) modulates the expression of genes involved in lipid and carbohydrate homeostasis and inflammatory processes. This nuclear receptor is likely a tumor suppressor in several cancers, but its molecular mechanism of suppression is still under study. Several studies reported tha...

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Detalles Bibliográficos
Autores principales:	Jose, Sandra, Devi, Sreevidya S., Sajeev, Anjana, Girisa, Sosmitha, Alqahtani, Mohammed S., Abbas, Mohamed, Alshammari, Abdulrahman, Sethi, Gautam, Kunnumakkara, Ajaikumar B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Portland Press Ltd. 2023
Materias:	Bioinformatics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9977715/ https://www.ncbi.nlm.nih.gov/pubmed/35348180 http://dx.doi.org/10.1042/BSR20212791

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