Transgenic NADH dehydrogenase restores oxygen regulation of breathing in mitochondrial complex I-deficient mice

The hypoxic ventilatory response (HVR) is a life-saving reflex, triggered by the activation of chemoreceptor glomus cells in the carotid body (CB) connected with the brainstem respiratory center. The molecular mechanisms underlying glomus cell acute oxygen (O(2)) sensing are unclear. Genetic disrupt...

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Detalles Bibliográficos
Autores principales: Jiménez-Gómez, Blanca, Ortega-Sáenz, Patricia, Gao, Lin, González-Rodríguez, Patricia, García-Flores, Paula, Chandel, Navdeep, López-Barneo, José
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9977773/
https://www.ncbi.nlm.nih.gov/pubmed/36859533
http://dx.doi.org/10.1038/s41467-023-36894-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9977773/
https://www.ncbi.nlm.nih.gov/pubmed/36859533
http://dx.doi.org/10.1038/s41467-023-36894-2

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