Cargando…

In situ single-crystal synchrotron X-ray diffraction studies of biologically active gases in metal-organic frameworks

Metal-organic frameworks (MOFs) are well known for their ability to adsorb various gases. The use of MOFs for the storage and release of biologically active gases, particularly nitric oxide (NO) and carbon monoxide (CO), has been a subject of interest. To elucidate the binding mechanisms and geometr...

Descripción completa

Detalles Bibliográficos
Autores principales: Main, Russell M., Vornholt, Simon M., Rice, Cameron M., Elliott, Caroline, Russell, Samantha E., Kerr, Peter J., Warren, Mark R., Morris, Russell E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9977776/
https://www.ncbi.nlm.nih.gov/pubmed/36859657
http://dx.doi.org/10.1038/s42004-023-00845-1
_version_ 1784899368114978816
author Main, Russell M.
Vornholt, Simon M.
Rice, Cameron M.
Elliott, Caroline
Russell, Samantha E.
Kerr, Peter J.
Warren, Mark R.
Morris, Russell E.
author_facet Main, Russell M.
Vornholt, Simon M.
Rice, Cameron M.
Elliott, Caroline
Russell, Samantha E.
Kerr, Peter J.
Warren, Mark R.
Morris, Russell E.
author_sort Main, Russell M.
collection PubMed
description Metal-organic frameworks (MOFs) are well known for their ability to adsorb various gases. The use of MOFs for the storage and release of biologically active gases, particularly nitric oxide (NO) and carbon monoxide (CO), has been a subject of interest. To elucidate the binding mechanisms and geometry of these gases, an in situ single crystal X-ray diffraction (scXRD) study using synchrotron radiation at Diamond Light Source has been performed on a set of MOFs that display promising gas adsorption properties. NO and CO, were introduced into activated Ni-CPO-27 and the related Co-4,6-dihydroxyisophthalate (Co-4,6-dhip). Both MOFs show strong binding affinity towards CO and NO, however CO suffers more from competitive co-adsorption of water. Additionally, we show that morphology can play an important role in the ease of dehydration for these two systems.
format Online
Article
Text
id pubmed-9977776
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher Nature Publishing Group UK
record_format MEDLINE/PubMed
spelling pubmed-99777762023-03-03 In situ single-crystal synchrotron X-ray diffraction studies of biologically active gases in metal-organic frameworks Main, Russell M. Vornholt, Simon M. Rice, Cameron M. Elliott, Caroline Russell, Samantha E. Kerr, Peter J. Warren, Mark R. Morris, Russell E. Commun Chem Article Metal-organic frameworks (MOFs) are well known for their ability to adsorb various gases. The use of MOFs for the storage and release of biologically active gases, particularly nitric oxide (NO) and carbon monoxide (CO), has been a subject of interest. To elucidate the binding mechanisms and geometry of these gases, an in situ single crystal X-ray diffraction (scXRD) study using synchrotron radiation at Diamond Light Source has been performed on a set of MOFs that display promising gas adsorption properties. NO and CO, were introduced into activated Ni-CPO-27 and the related Co-4,6-dihydroxyisophthalate (Co-4,6-dhip). Both MOFs show strong binding affinity towards CO and NO, however CO suffers more from competitive co-adsorption of water. Additionally, we show that morphology can play an important role in the ease of dehydration for these two systems. Nature Publishing Group UK 2023-03-01 /pmc/articles/PMC9977776/ /pubmed/36859657 http://dx.doi.org/10.1038/s42004-023-00845-1 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Main, Russell M.
Vornholt, Simon M.
Rice, Cameron M.
Elliott, Caroline
Russell, Samantha E.
Kerr, Peter J.
Warren, Mark R.
Morris, Russell E.
In situ single-crystal synchrotron X-ray diffraction studies of biologically active gases in metal-organic frameworks
title In situ single-crystal synchrotron X-ray diffraction studies of biologically active gases in metal-organic frameworks
title_full In situ single-crystal synchrotron X-ray diffraction studies of biologically active gases in metal-organic frameworks
title_fullStr In situ single-crystal synchrotron X-ray diffraction studies of biologically active gases in metal-organic frameworks
title_full_unstemmed In situ single-crystal synchrotron X-ray diffraction studies of biologically active gases in metal-organic frameworks
title_short In situ single-crystal synchrotron X-ray diffraction studies of biologically active gases in metal-organic frameworks
title_sort in situ single-crystal synchrotron x-ray diffraction studies of biologically active gases in metal-organic frameworks
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9977776/
https://www.ncbi.nlm.nih.gov/pubmed/36859657
http://dx.doi.org/10.1038/s42004-023-00845-1
work_keys_str_mv AT mainrussellm insitusinglecrystalsynchrotronxraydiffractionstudiesofbiologicallyactivegasesinmetalorganicframeworks
AT vornholtsimonm insitusinglecrystalsynchrotronxraydiffractionstudiesofbiologicallyactivegasesinmetalorganicframeworks
AT ricecameronm insitusinglecrystalsynchrotronxraydiffractionstudiesofbiologicallyactivegasesinmetalorganicframeworks
AT elliottcaroline insitusinglecrystalsynchrotronxraydiffractionstudiesofbiologicallyactivegasesinmetalorganicframeworks
AT russellsamanthae insitusinglecrystalsynchrotronxraydiffractionstudiesofbiologicallyactivegasesinmetalorganicframeworks
AT kerrpeterj insitusinglecrystalsynchrotronxraydiffractionstudiesofbiologicallyactivegasesinmetalorganicframeworks
AT warrenmarkr insitusinglecrystalsynchrotronxraydiffractionstudiesofbiologicallyactivegasesinmetalorganicframeworks
AT morrisrusselle insitusinglecrystalsynchrotronxraydiffractionstudiesofbiologicallyactivegasesinmetalorganicframeworks