Honokiol suppresses the aberrant interactions between renal resident macrophages and tubular epithelial cells in lupus nephritis through the NLRP3/IL-33/ST2 axis

Lupus nephritis (LN) is a type of immune-complex nephritis caused by systemic lupus erythematosus and is a major contributor to mortality and morbidity. Honokiol (HNK) has been found to have a therapeutic effect on LN, but its action mechanism remains unclear. In this study, we first demonstrated th...

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Detalles Bibliográficos
Autores principales: Ma, Qing, Xu, Mengyang, Jing, Xin, Qiu, Jiang, Huang, Shuo, Yan, Honghao, Yin, Lu, Lou, Jiang, Zhao, Lisha, Fan, Yongsheng, Qiu, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9977833/
https://www.ncbi.nlm.nih.gov/pubmed/36859530
http://dx.doi.org/10.1038/s41419-023-05680-9

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