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Metastasectomy of a solitary liver tumor from prostate cancer after radical prostatectomy

INTRODUCTION: Metastasectomy of oligometastatic prostate cancer has the potential to contribute to improving prognosis. We report on a case of metastasectomy of solitary liver tumor after radical prostatectomy. CASE PRESENTATION: An 80‐year‐old man underwent radical prostatectomy for prostate cancer...

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Autores principales: Hayashi, Tomoyuki, Yoshida, Kenji, Tamura, Chiharu, Miyazawa, Yoshio, Sato, Masahiko, Miyamoto, Taito, Nakagawa, Masayuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9978059/
https://www.ncbi.nlm.nih.gov/pubmed/36875001
http://dx.doi.org/10.1002/iju5.12561
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author Hayashi, Tomoyuki
Yoshida, Kenji
Tamura, Chiharu
Miyazawa, Yoshio
Sato, Masahiko
Miyamoto, Taito
Nakagawa, Masayuki
author_facet Hayashi, Tomoyuki
Yoshida, Kenji
Tamura, Chiharu
Miyazawa, Yoshio
Sato, Masahiko
Miyamoto, Taito
Nakagawa, Masayuki
author_sort Hayashi, Tomoyuki
collection PubMed
description INTRODUCTION: Metastasectomy of oligometastatic prostate cancer has the potential to contribute to improving prognosis. We report on a case of metastasectomy of solitary liver tumor after radical prostatectomy. CASE PRESENTATION: An 80‐year‐old man underwent radical prostatectomy for prostate cancer, followed by radiotherapy after the operation because of increased serum prostate‐specific antigen levels of 0.529 ng/mL. Levels increased further to 0.997 ng/mL even after salvage therapy. The patient then received androgen deprivation therapy. Levels remained stable for 3 years, but rapidly increased to 19.781 ng/mL in the following 6 months. Abdominal computed tomography revealed a solitary liver tumor, and no metastasis to other sites was identified. The patient underwent liver segmentectomy. Microscopic examination of excised specimens revealed prostate cancer cells. Five years after surgery, serum prostate‐specific antigen maintained to the lowest level so far. CONCLUSION: Metastasectomy might be a beneficial therapeutic option to improve the prognosis for solitary metastasis from prostate cancer.
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spelling pubmed-99780592023-03-03 Metastasectomy of a solitary liver tumor from prostate cancer after radical prostatectomy Hayashi, Tomoyuki Yoshida, Kenji Tamura, Chiharu Miyazawa, Yoshio Sato, Masahiko Miyamoto, Taito Nakagawa, Masayuki IJU Case Rep Case Reports INTRODUCTION: Metastasectomy of oligometastatic prostate cancer has the potential to contribute to improving prognosis. We report on a case of metastasectomy of solitary liver tumor after radical prostatectomy. CASE PRESENTATION: An 80‐year‐old man underwent radical prostatectomy for prostate cancer, followed by radiotherapy after the operation because of increased serum prostate‐specific antigen levels of 0.529 ng/mL. Levels increased further to 0.997 ng/mL even after salvage therapy. The patient then received androgen deprivation therapy. Levels remained stable for 3 years, but rapidly increased to 19.781 ng/mL in the following 6 months. Abdominal computed tomography revealed a solitary liver tumor, and no metastasis to other sites was identified. The patient underwent liver segmentectomy. Microscopic examination of excised specimens revealed prostate cancer cells. Five years after surgery, serum prostate‐specific antigen maintained to the lowest level so far. CONCLUSION: Metastasectomy might be a beneficial therapeutic option to improve the prognosis for solitary metastasis from prostate cancer. John Wiley and Sons Inc. 2022-12-10 /pmc/articles/PMC9978059/ /pubmed/36875001 http://dx.doi.org/10.1002/iju5.12561 Text en © 2022 The Authors. IJU Case Reports published by John Wiley & Sons Australia, Ltd on behalf of Japanese Urological Association. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Reports
Hayashi, Tomoyuki
Yoshida, Kenji
Tamura, Chiharu
Miyazawa, Yoshio
Sato, Masahiko
Miyamoto, Taito
Nakagawa, Masayuki
Metastasectomy of a solitary liver tumor from prostate cancer after radical prostatectomy
title Metastasectomy of a solitary liver tumor from prostate cancer after radical prostatectomy
title_full Metastasectomy of a solitary liver tumor from prostate cancer after radical prostatectomy
title_fullStr Metastasectomy of a solitary liver tumor from prostate cancer after radical prostatectomy
title_full_unstemmed Metastasectomy of a solitary liver tumor from prostate cancer after radical prostatectomy
title_short Metastasectomy of a solitary liver tumor from prostate cancer after radical prostatectomy
title_sort metastasectomy of a solitary liver tumor from prostate cancer after radical prostatectomy
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9978059/
https://www.ncbi.nlm.nih.gov/pubmed/36875001
http://dx.doi.org/10.1002/iju5.12561
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