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A regressed germ cell tumor discovered secondary to azoospermia

INTRODUCTION: Regressed germ cell tumors are a rare disease commonly diagnosed with metastatic symptoms without local symptoms in the testis. CASE PRESENTATION: A 33‐year‐old man with azoospermia was referred to our hospital. His right testis was slightly swollen, and ultrasonography revealed hypoec...

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Autores principales: Tsujioka, Hiroki, Uemura, Keiichiro, Iwahata, Toshiyuki, Inoue, Yasuyuki, Inoue, Minoru, Osaka, Akiyoshi, Nakayama, Akinori, Okada, Hiroshi, Saito, Kazutaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9978086/
https://www.ncbi.nlm.nih.gov/pubmed/36874990
http://dx.doi.org/10.1002/iju5.12552
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author Tsujioka, Hiroki
Uemura, Keiichiro
Iwahata, Toshiyuki
Inoue, Yasuyuki
Inoue, Minoru
Osaka, Akiyoshi
Nakayama, Akinori
Okada, Hiroshi
Saito, Kazutaka
author_facet Tsujioka, Hiroki
Uemura, Keiichiro
Iwahata, Toshiyuki
Inoue, Yasuyuki
Inoue, Minoru
Osaka, Akiyoshi
Nakayama, Akinori
Okada, Hiroshi
Saito, Kazutaka
author_sort Tsujioka, Hiroki
collection PubMed
description INTRODUCTION: Regressed germ cell tumors are a rare disease commonly diagnosed with metastatic symptoms without local symptoms in the testis. CASE PRESENTATION: A 33‐year‐old man with azoospermia was referred to our hospital. His right testis was slightly swollen, and ultrasonography revealed hypoechogenicity of the right testis with decreased blood flow. Right high orchiectomy was performed. Pathologically, the seminiferous tubules were absent or highly atrophied with vitrification degeneration; however, no neoplastic lesion was confirmed. One‐month post‐surgery, the patient noticed a mass in the left supraclavicular fossa, of which a biopsy revealed seminoma. The patient was diagnosed with a regressed germ cell tumor and underwent systemic chemotherapy. CONCLUSION: We reported the first case of a regressed germ cell tumor discovered due to complaints of azoospermia.
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spelling pubmed-99780862023-03-03 A regressed germ cell tumor discovered secondary to azoospermia Tsujioka, Hiroki Uemura, Keiichiro Iwahata, Toshiyuki Inoue, Yasuyuki Inoue, Minoru Osaka, Akiyoshi Nakayama, Akinori Okada, Hiroshi Saito, Kazutaka IJU Case Rep Case Reports INTRODUCTION: Regressed germ cell tumors are a rare disease commonly diagnosed with metastatic symptoms without local symptoms in the testis. CASE PRESENTATION: A 33‐year‐old man with azoospermia was referred to our hospital. His right testis was slightly swollen, and ultrasonography revealed hypoechogenicity of the right testis with decreased blood flow. Right high orchiectomy was performed. Pathologically, the seminiferous tubules were absent or highly atrophied with vitrification degeneration; however, no neoplastic lesion was confirmed. One‐month post‐surgery, the patient noticed a mass in the left supraclavicular fossa, of which a biopsy revealed seminoma. The patient was diagnosed with a regressed germ cell tumor and underwent systemic chemotherapy. CONCLUSION: We reported the first case of a regressed germ cell tumor discovered due to complaints of azoospermia. John Wiley and Sons Inc. 2022-11-08 /pmc/articles/PMC9978086/ /pubmed/36874990 http://dx.doi.org/10.1002/iju5.12552 Text en © 2022 The Authors. IJU Case Reports published by John Wiley & Sons Australia, Ltd on behalf of Japanese Urological Association. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Reports
Tsujioka, Hiroki
Uemura, Keiichiro
Iwahata, Toshiyuki
Inoue, Yasuyuki
Inoue, Minoru
Osaka, Akiyoshi
Nakayama, Akinori
Okada, Hiroshi
Saito, Kazutaka
A regressed germ cell tumor discovered secondary to azoospermia
title A regressed germ cell tumor discovered secondary to azoospermia
title_full A regressed germ cell tumor discovered secondary to azoospermia
title_fullStr A regressed germ cell tumor discovered secondary to azoospermia
title_full_unstemmed A regressed germ cell tumor discovered secondary to azoospermia
title_short A regressed germ cell tumor discovered secondary to azoospermia
title_sort regressed germ cell tumor discovered secondary to azoospermia
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9978086/
https://www.ncbi.nlm.nih.gov/pubmed/36874990
http://dx.doi.org/10.1002/iju5.12552
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