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Genetic background strongly influences the transition to chronic kidney disease of adriamycin nephropathy in mice

Animal models of podocytopathy and chronic kidney diseases (CKD) help elucidate these pathologies. Adriamycin (ADR)-induced nephropathy is a common rodent model of podocytopathy. BALB/c mice are sensitive to ADR, whereas C57BL/6 (B6) mice, the most commonly used strain, are resistant to ADR. Therefo...

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Detalles Bibliográficos
Autores principales: Watanabe, Masaki, Hiura, Koki, Sasaki, Hayato, Okamura, Tadashi, Sasaki, Nobuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Association for Laboratory Animal Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9978128/
https://www.ncbi.nlm.nih.gov/pubmed/36058845
http://dx.doi.org/10.1538/expanim.22-0057