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Donor derived hematopoietic stem cell niche transplantation facilitates mixed chimerism mediated donor specific tolerance

Compelling experimental evidence confirms that the robustness and longevity of mixed chimerism (MC) relies on the persistence and availability of donor-derived hematopoietic stem cell (HSC) niches in recipients. Based on our prior work in rodent vascularized composite allotransplantation (VCA) model...

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Detalles Bibliográficos
Autores principales: Zhang, Wensheng, Wang, Yong, Zhong, Fushun, Wang, Xinghuan, Sucher, Robert, Lin, Cheng-Hung, Brandacher, Gerald, Solari, Mario G., Gorantla, Vijay S., Zheng, Xin Xiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9978155/
https://www.ncbi.nlm.nih.gov/pubmed/36875068
http://dx.doi.org/10.3389/fimmu.2023.1093302