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Donor derived hematopoietic stem cell niche transplantation facilitates mixed chimerism mediated donor specific tolerance
Compelling experimental evidence confirms that the robustness and longevity of mixed chimerism (MC) relies on the persistence and availability of donor-derived hematopoietic stem cell (HSC) niches in recipients. Based on our prior work in rodent vascularized composite allotransplantation (VCA) model...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9978155/ https://www.ncbi.nlm.nih.gov/pubmed/36875068 http://dx.doi.org/10.3389/fimmu.2023.1093302 |