Cargando…

BRCA1 interactors, RAD50 and BRIP1, as prognostic markers for triple-negative breast cancer severity

Introduction: BRIP1 (BRCA1-interacting protein 1) is one of the major interacting partners of BRCA1, which plays an important role in repair by homologous recombination (HR). This gene is mutated in around 4% of cases of breast cancer; however, its mechanism of action is unclear. In this study, we p...

Descripción completa

Detalles Bibliográficos
Autores principales:	Katheeja, Muhseena N., Das, Shankar Prasad, Das, Ranajit, Laha, Suparna
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9978165/ https://www.ncbi.nlm.nih.gov/pubmed/36873936 http://dx.doi.org/10.3389/fgene.2023.1035052

Ejemplares similares

The budding yeast protein Chl1p is required for delaying progression through G1/S phase after DNA damage
por: Katheeja, Muhseena N., et al.
Publicado: (2021)

The repair gene BACH1 - a potential oncogene
por: Muhseena N, Katheeja, et al.
Publicado: (2021)

Screening for BRCA1, BRCA2, CHEK2, PALB2, BRIP1, RAD50, and CDH1 mutations in high-risk Finnish BRCA1/2-founder mutation-negative breast and/or ovarian cancer individuals
por: Kuusisto, Kirsi M, et al.
Publicado: (2011)

FOXO3a Mediates Homologous Recombination Repair (HRR) via Transcriptional Activation of MRE11, BRCA1, BRIP1, and RAD50
por: Inci, Gozde, et al.
Publicado: (2022)

Identification of Novel BRCA1 and RAD50 Mutations Associated With Breast Cancer Predisposition in Tunisian Patients
por: Mighri, Najah, et al.
Publicado: (2020)

Genetic Susceptibility to Fungal Infections and Links to Human Ancestry
por: Naik, Bharati, et al.
Publicado: (2021)

BRCA1 testing should be offered to individuals with triple-negative breast cancer diagnosed below 50 years
por: Robertson, L, et al.
Publicado: (2012)

Mutation status of RAD51C,PALB2 and BRIP1 in 100 Japanese familial breast cancer cases without BRCA1 and BRCA2 mutations
por: Sato, Katsutoshi, et al.
Publicado: (2017)

Clinical importance of FANCD2, BRIP1, BRCA1, BRCA2 and FANCF expression in ovarian carcinomas
por: Moes-Sosnowska, Joanna, et al.
Publicado: (2019)

Functional Interaction Between BRCA1 and DNA Repair in Yeast May Uncover a Role of RAD50, RAD51, MRE11A, and MSH6 Somatic Variants in Cancer Development
por: Maresca, Luisa, et al.
Publicado: (2018)

Analysis of BRIP1 Variants among Korean Patients with BRCA1/2 Mutation-Negative High-Risk Breast Cancer
por: Kim, Haeyoung, et al.
Publicado: (2016)

Loss of the BRCA1-Interacting Helicase BRIP1 Results in Abnormal Mammary Acinar Morphogenesis
por: Daino, Kazuhiro, et al.
Publicado: (2013)

A recurrent truncating germline mutation in the BRIP1/FANCJ gene and susceptibility to prostate cancer
por: Kote-Jarai, Z, et al.
Publicado: (2009)

Triple-negative breast cancer: BRCAness and concordance of clinical features with BRCA1-mutation carriers
por: Lips, E H, et al.
Publicado: (2013)

Absence of truncating BRIP1 mutations in chromosome 17q-linked hereditary prostate cancer families
por: Ray, A M, et al.
Publicado: (2009)

Novel role of BRCA1 interacting C‐terminal helicase 1 (BRIP1) in breast tumour cell invasion
por: Rizeq, Balsam, et al.
Publicado: (2020)

The budding yeast protein Chl1p is required to preserve genome integrity upon DNA damage in S-phase
por: Laha, Suparna, et al.
Publicado: (2006)

A single-nucleotide polymorphism in the RAD51 gene modifies breast cancer risk in BRCA2 carriers, but not in BRCA1 carriers or noncarriers
por: Kadouri, L, et al.
Publicado: (2004)

Exome Sequencing in BRCA1- and BRCA2-Negative Greek Families Identifies MDM1 and NBEAL1 as Candidate Risk Genes for Hereditary Breast Cancer
por: Glentis, Stavros, et al.
Publicado: (2019)

Epigenetic Inactivation of the BRCA1 Interactor SRBC and Resistance to Oxaliplatin in Colorectal Cancer
por: Moutinho, Catia, et al.
Publicado: (2013)

Age of ovarian cancer diagnosis among BRIP1, RAD51C, and RAD51D mutation carriers identified through multi-gene panel testing
por: Cummings, Shelly, et al.
Publicado: (2021)

Multimolecular characteristics and role of BRCA1 interacting protein C-terminal helicase 1 (BRIP1) in human tumors: a pan-cancer analysis
por: Wang, Ruohuang, et al.
Publicado: (2023)

Using Ancestry Informative Markers (AIMs) to Detect Fine Structures Within Gorilla Populations
por: Das, Ranajit, et al.
Publicado: (2019)

Post-translational Modification Crosstalk and Hotspots in Sirtuin Interactors Implicated in Cardiovascular Diseases
por: Aggarwal, Suruchi, et al.
Publicado: (2020)

The Origins of Ashkenaz, Ashkenazic Jews, and Yiddish
por: Das, Ranajit, et al.
Publicado: (2017)

Editorial: Individual and population-specific variation in cancer susceptibility, prevalence, and disease presentation
por: Mustak, Mohammed S., et al.
Publicado: (2023)

BRCA1 mutation in the Triple- Negative Breast Cancer Group
por: Maksimenko, Jelena, et al.
Publicado: (2012)

Comprehensive molecular comparison of BRCA1 hypermethylated and BRCA1 mutated triple negative breast cancers
por: Glodzik, Dominik, et al.
Publicado: (2020)

UK consensus recommendations for clinical management of cancer risk for women with germline pathogenic variants in cancer predisposition genes: RAD51C, RAD51D, BRIP1 and PALB2
por: Hanson, Helen, et al.
Publicado: (2023)

BRCA1-methylated triple negative breast cancers previously exposed to neoadjuvant chemotherapy form RAD51 foci and respond poorly to olaparib
por: Velazquez, Carolina, et al.
Publicado: (2023)

Functional characterization of the Saccharomyces cerevisiae protein Chl1 reveals the role of sister chromatid cohesion in the maintenance of spindle length during S-phase arrest
por: Laha, Suparna, et al.
Publicado: (2011)

Detection of loss of heterozygosity at RAD51, RAD52, RAD54 and BRCA1 and BRCA2 loci in breast cancer: pathological correlations
por: Gonzalez, R, et al.
Publicado: (1999)

BRCA-1 and BRCA-2 mutation bedside detection and breast cancer clinical primary prevention
por: Stagnaro, Sergio, et al.
Publicado: (2013)

Male Triple-Negative Breast Cancer
por: Qavi, Qasif, et al.
Publicado: (2021)

BRCA1 and BRCA2 mutations in Scotland and Northern Ireland
Publicado: (2003)

Design and validation of a next generation sequencing assay for hereditary BRCA1 and BRCA2 mutation testing
por: Kang, Hyunseok P., et al.
Publicado: (2016)

Olaparib Monotherapy for BRIP1-Mutated High-Grade Serous Endometrial Cancer
por: Nakamura, Kohei, et al.
Publicado: (2020)

BRIP1, RAD51C, and RAD51D mutations are associated with high susceptibility to ovarian cancer: mutation prevalence and precise risk estimates based on a pooled analysis of ~30,000 cases
por: Suszynska, Malwina, et al.
Publicado: (2020)

Editorial: Association Between Individuals’ Genomic Ancestry and Variation in Disease Susceptibility
por: Das, Ranajit, et al.
Publicado: (2022)

Editorial: Population and ancestry specific variation in disease susceptibility
por: Das, Ranajit, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_4fte48ndq7tp78vc12vceu412b