Predicting treatment response to vancomycin using bacterial DNA load as a pharmacodynamic marker in premature and very low birth weight neonates: A population PKPD study

Background: While positive blood cultures are the gold standard for late-onset sepsis (LOS) diagnosis in premature and very low birth weight (VLBW) newborns, these results can take days, and early markers of possible treatment efficacy are lacking. The objective of the present study was to investiga...

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Detalles Bibliográficos
Autores principales: Samb, Amadou, De Kroon, Rimke, Dijkstra, Koos, Van Den Brand, Marre, Bos, Martine, Van Den Dungen, Frank, Veldkamp, Agnes, Wilhelm, Bram, De Haan, Timo R., Bijleveld, Yuma A., Tutu Van Furth, Marceline, Savelkoul, Paul, Swart, Noortje, Mathot, Ron, Van Weissenbruch, Mirjam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9978179/
https://www.ncbi.nlm.nih.gov/pubmed/36873984
http://dx.doi.org/10.3389/fphar.2023.1104482

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