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Efficacy of Omadacycline or Vancomycin Combined With Germinants for Preventing Clostridioides difficile Relapse in a Murine Model

BACKGROUND: Clostridioides difficile infections (CDI) and recurrence (rCDI) are major health care burdens. Recurrence is likely caused by spores in the gastrointestinal tract that germinate after antibiotic therapy. This murine study explores germinant-antibiotic combinations for CDI. METHODS: Previ...

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Detalles Bibliográficos
Autores principales:	Budi, Noah D, Godfrey, Jared J, Safdar, Nasia, Shukla, Sanjay K, Rose, Warren E
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2022
Materias:	Major Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9978312/ https://www.ncbi.nlm.nih.gov/pubmed/35904942 http://dx.doi.org/10.1093/infdis/jiac324

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