Why loss of Y? A pan-cancer genome analysis of tumors with loss of Y chromosome

Loss of the Y chromosome (LoY) is frequently observed in somatic cells of elderly men. However, LoY is highly increased in tumor tissue and correlates with an overall worse prognosis. The underlying causes and downstream effects of LoY are widely unknown. Therefore, we analyzed genomic and transcrip...

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Detalles Bibliográficos
Autores principales: Müller, Philipp, Velazquez Camacho, Oscar, Yazbeck, Ali M., Wölwer, Christina, Zhai, Weiwei, Schumacher, Johannes, Heider, Dominik, Buettner, Reinhard, Quaas, Alexander, Hillmer, Axel M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9978323/
https://www.ncbi.nlm.nih.gov/pubmed/36874157
http://dx.doi.org/10.1016/j.csbj.2023.02.024

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