Cargando…
α-Kleisin subunit of cohesin preserves the genome integrity of embryonic stem cells
Cohesin is a ring-shaped protein complex that comprises the SMC1, SMC3, and α-kleisin proteins, STAG1/2/3 subunits, and auxiliary factors. Cohesin participates in chromatin remodeling, chromosome segregation, DNA replication, and gene expression regulation during the cell cycle. Mitosis-specific α-k...
Autores principales: | Yoon, Seobin, Choi, Eui-Hwan, Park, Seo Jung, Kim, Keun Pil |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Korean Society for Biochemistry and Molecular Biology
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9978357/ https://www.ncbi.nlm.nih.gov/pubmed/36571142 http://dx.doi.org/10.5483/BMBRep.2022-0106 |
Ejemplares similares
-
The Kleisin Subunits of Cohesin Are Involved in the Fate Determination of Embryonic Stem Cells
por: Koh, Young Eun, et al.
Publicado: (2022) -
Maintenance of genome integrity and active homologous recombination in embryonic stem cells
por: Choi, Eui-Hwan, et al.
Publicado: (2020) -
Divergent kleisin subunits of cohesin specify mechanisms to tether and release meiotic chromosomes
por: Severson, Aaron F, et al.
Publicado: (2014) -
Meiosis-specific cohesin complexes display essential and distinct roles in mitotic embryonic stem cell chromosomes
por: Choi, Eui-Hwan, et al.
Publicado: (2022) -
The structure of the cohesin ATPase elucidates the mechanism of SMC–kleisin ring opening
por: Muir, Kyle W., et al.
Publicado: (2020)