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KPNA3 promotes epithelial-mesenchymal transition by regulating TGF-β and AKT signaling pathways in MDA-MB-231, a triple-negative breast cancer cell line

Karyopherin-α3 (KPNA3), a karyopherin-α isoform, is intimately associated with metastatic progression via epithelial-mesenchymal transition (EMT). However, the molecular mechanism underlying how KPNA3 acts as an EMT inducer remains to be elucidated. In this report, we identified that KPNA3 was signi...

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Detalles Bibliográficos
Autores principales:	Choi, Jaesung, Choi, Jee-Hye, Lee, Ho Woon, Seo, Dongbeom, Lkhagvasuren, Gavaachimed, Kim, Jung-Woong, Seo, Sang-Beom, Lee, Kangseok, Lee, Kwang-Ho
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Korean Society for Biochemistry and Molecular Biology 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9978358/ https://www.ncbi.nlm.nih.gov/pubmed/36593106 http://dx.doi.org/10.5483/BMBRep.2022-0180

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