Cargando…

AMPK-induced mitochondrial biogenesis decelerates retinal pigment epithelial cell degeneration under nutrient starvation

The implications of nutrient starvation due to aging on the degeneration of the retinal pigment epithelium (RPE) is yet to be fully explored. We examined the involvement of AMPK activation in mitochondrial homeostasis and its relationship with the maintenance of a healthy mitochondrial population an...

Descripción completa

Detalles Bibliográficos
Autores principales:	Park, Yujin, Jeong, Yeeun, Son, Sumin, Kim, Dong-Eun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Korean Society for Biochemistry and Molecular Biology 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9978359/ https://www.ncbi.nlm.nih.gov/pubmed/36195569 http://dx.doi.org/10.5483/BMBRep.2022-0125

Ejemplares similares

Paraoxonase 2 Deficiency Causes Mitochondrial Dysfunction in Retinal Pigment Epithelial Cells and Retinal Degeneration in Mice
por: Sreekumar, Parameswaran Gangadharan, et al.
Publicado: (2023)

Role of Mitochondria in Retinal Pigment Epithelial Aging and Degeneration
por: Tong, Yao, et al.
Publicado: (2022)

Retinal Pigment Epithelial Detachment in Age-Related Macular Degeneration
por: Karampelas, Michael, et al.
Publicado: (2020)

Induced retinal pigment epithelial cells with anti-epithelial-to-mesenchymal transition ability delay retinal degeneration
por: Tian, Haibin, et al.
Publicado: (2022)

Retinal pigment epithelial tears following ranibizumab therapy for fibrovascular retinal pigment epithelial detachment due to occult age-related macular degeneration
por: Figurska, Małgorzata
Publicado: (2012)

Effects of Isorhamnetin on Adipocyte Mitochondrial Biogenesis and AMPK Activation
por: Lee, Mak-Soon, et al.
Publicado: (2018)

Evaluation of retinal pigment epithelium changes in serous pigment epithelial detachment in age-related macular degeneration
por: Miura, Masahiro, et al.
Publicado: (2021)

Retinal pigment epithelial detachments and tears, and progressive retinal degeneration in light chain deposition disease
por: Spielberg, Leigh H, et al.
Publicado: (2013)

Scaffolds for retinal pigment epithelial cell transplantation in age-related macular degeneration
por: White, Corina E, et al.
Publicado: (2017)

Hydroquinone predisposes for retinal pigment epithelial (RPE) cell degeneration in inflammatory conditions
por: Bhattarai, Niina, et al.
Publicado: (2022)

Depletion of Mitochondrial DNA in Differentiated Retinal Pigment Epithelial Cells
por: Hu, Xinqian, et al.
Publicado: (2019)

Aldose reductase inhibition decelerates optic nerve degeneration by alleviating retinal microglia activation
por: Rao, Mishal, et al.
Publicado: (2023)

Nutrient deprivation and lysosomal stress induce activation of TFEB in retinal pigment epithelial cells
por: Pan, Hsuan-Yeh, et al.
Publicado: (2019)

Retinal Pigment Epithelial and Outer Retinal Atrophy in Age-Related Macular Degeneration: Correlation with Macular Function
por: Savastano, Maria C., et al.
Publicado: (2020)

Human Amniotic Epithelial Stem Cell-Derived Retinal Pigment Epithelium Cells Repair Retinal Degeneration
por: Li, Jinying, et al.
Publicado: (2021)

Treatment of retinal pigment epithelial detachment secondary to exudative age-related macular degeneration
por: Gonzalez, Andres, et al.
Publicado: (2017)

The Role of Retinal Pigment Epithelial Cells in Age-Related Macular Degeneration: Phagocytosis and Autophagy
por: Si, Zhibo, et al.
Publicado: (2023)

Involvement of the Retinal Pigment Epithelium in the Development of Retinal Lattice Degeneration
por: Mizuno, Hiroshi, et al.
Publicado: (2020)

Chorioretinal thickness and retinal pigment epithelial degeneration of fellow eyes in patients with unilateral neovascular age-related macular degeneration with subretinal drusenoid deposits
por: Kang, Dongwan, et al.
Publicado: (2022)

Spatiotemporal roles of AMPK in PARP-1- and autophagy-dependent retinal pigment epithelial cell death caused by UVA
por: Wu, Anthony Yan-Tang, et al.
Publicado: (2023)

Etoposide Induces ATM-Dependent Mitochondrial Biogenesis through AMPK Activation
por: Fu, Xuan, et al.
Publicado: (2008)

The hypoglycemic mechanism of catalpol involves increased AMPK-mediated mitochondrial biogenesis
por: Xu, Deng-qiu, et al.
Publicado: (2020)

AMPK promotes lysosomal and mitochondrial biogenesis via folliculin:FNIP1
por: Freemantle, Jordana B, et al.
Publicado: (2023)

Progression of Retinal Pigment Epithelial Atrophy in Antiangiogenic Therapy of Neovascular Age-Related Macular Degeneration
por: Schütze, Christopher, et al.
Publicado: (2015)

Hypoxia-induced metabolic stress in retinal pigment epithelial cells is sufficient to induce photoreceptor degeneration
por: Kurihara, Toshihide, et al.
Publicado: (2016)

Transplantation of Human Embryonic Stem Cell-Derived Retinal Pigment Epithelial Cells in Macular Degeneration
por: Mehat, Manjit S., et al.
Publicado: (2018)

Hyperhomocysteinemia disrupts retinal pigment epithelial structure and function with features of age-related macular degeneration
por: Ibrahim, Ahmed S., et al.
Publicado: (2016)

Direct conversion of human umbilical cord mesenchymal stem cells into retinal pigment epithelial cells for treatment of retinal degeneration
por: Zhu, Xiaoman, et al.
Publicado: (2022)

Metformin inhibits methylglyoxal-induced retinal pigment epithelial cell death and retinopathy via AMPK-dependent mechanisms: Reversing mitochondrial dysfunction and upregulating glyoxalase 1
por: Sekar, Ponarulselvam, et al.
Publicado: (2023)

Crosstalk between Aryl Hydrocarbon Receptor and Glucocorticoid Receptor in Human Retinal Pigment Epithelial Cells
por: Jin, Hong Lan, et al.
Publicado: (2017)

Serpentine retinal pigment epithelial tear
por: Maitray, Aditya, et al.
Publicado: (2021)

Human retinal pigment epithelial cells
por: Wang, Lei, et al.
Publicado: (2021)

α–SNAP inhibits AMPK signaling to reduce mitochondrial biogenesis and dephosphorylates Thr172 in AMPKα in vitro
por: Wang, Lifu, et al.
Publicado: (2013)

Retinal pigment epithelial tears after intravitreal bevacizumab injection for exudative age-related macular degeneration
por: Shaikh, Saad, et al.
Publicado: (2007)

Retinal pigment epithelial tear after intravitreal bevacizumab injection for exudative age-related macular degeneration
por: Singh, Sunil Kumar, et al.
Publicado: (2014)

Detrimental Effects of UVB on Retinal Pigment Epithelial Cells and Its Role in Age-Related Macular Degeneration
por: Mahendra, Camille Keisha, et al.
Publicado: (2020)

Human iPSC- and Primary-Retinal Pigment Epithelial Cells for Modeling Age-Related Macular Degeneration
por: Fisher, Cody R., et al.
Publicado: (2022)

AMPK activator decelerates osteoarthritis development by inhibition of β-catenin signaling in chondrocytes
por: Zhu, Zhenglin, et al.
Publicado: (2022)

Mechanisms of protection of retinal pigment epithelial cells from oxidant injury by humanin and other mitochondrial-derived peptides: Implications for age-related macular degeneration
por: Sreekumar, Parameswaran G., et al.
Publicado: (2020)

Effect of bevacizumab (Avastin™) on mitochondrial function of in vitro retinal pigment epithelial, neurosensory retinal and microvascular endothelial cells
por: Luthra, Saurabh, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_id4e40i85ds05pthmrrgciktrh