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Therapeutic effects of selective p300 histone acetyl-transferase inhibitor on liver fibrosis

Liver fibrosis is caused by chronic liver damage and results in the aberrant accumulation of extracellular matrix during disease progression. Despite the identification of the HAT enzyme p300 as a major factor for liver fibrosis, the development of therapeutic agents targeting the regulation of p300...

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Detalles Bibliográficos
Autores principales: Kim, Hyunsik, Park, Soo-Yeon, Lee, Soo Yeon, Kwon, Jae-Hwan, Byun, Seunghee, Kim, Mi Jeong, Yu, Sungryul, Yoo, Jung-Yoon, Yoon, Ho-Geun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9978366/
https://www.ncbi.nlm.nih.gov/pubmed/36593107
http://dx.doi.org/10.5483/BMBRep.2022-0188