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Evolutionarily conserved IL-27β enhances Th1 cells potential by triggering the JAK1/STAT1/T-bet axis in Nile tilapia

As a pleiotropic cytokine in the interleukin (IL)-12 family, IL-27β plays a significant role in regulating immune cell responses, eliminating invading pathogens, and maintaining immune homeostasis. Although non-mammalian IL-27β homologs have been identified, the mechanism of whether and how it is in...

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Detalles Bibliográficos
Autores principales: Geng, Ming, Li, Kang, Ai, Kete, Liang, Wei, Yang, Jialong, Wei, Xiumei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9978509/
https://www.ncbi.nlm.nih.gov/pubmed/36873098
http://dx.doi.org/10.1016/j.fsirep.2023.100087