An extensively validated whole-cell biosensor for specific, sensitive and high-throughput detection of antibacterial inhibitors targeting cell-wall biosynthesis

BACKGROUND: Whole-cell biosensor strains are powerful tools for antibacterial drug discovery, in principle allowing the identification of inhibitors acting on specific, high-value target pathways. Whilst a variety of biosensors have been described for detecting cell-wall biosynthesis inhibitors (CWB...

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Detalles Bibliográficos
Autores principales: Galarion, Luiza H, Mitchell, Jennifer K, Randall, Christopher P, O’Neill, Alex J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9978594/
https://www.ncbi.nlm.nih.gov/pubmed/36626387
http://dx.doi.org/10.1093/jac/dkac429

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9978594/
https://www.ncbi.nlm.nih.gov/pubmed/36626387
http://dx.doi.org/10.1093/jac/dkac429

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