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An extensively validated whole-cell biosensor for specific, sensitive and high-throughput detection of antibacterial inhibitors targeting cell-wall biosynthesis
BACKGROUND: Whole-cell biosensor strains are powerful tools for antibacterial drug discovery, in principle allowing the identification of inhibitors acting on specific, high-value target pathways. Whilst a variety of biosensors have been described for detecting cell-wall biosynthesis inhibitors (CWB...
Autores principales: | Galarion, Luiza H, Mitchell, Jennifer K, Randall, Christopher P, O’Neill, Alex J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9978594/ https://www.ncbi.nlm.nih.gov/pubmed/36626387 http://dx.doi.org/10.1093/jac/dkac429 |
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