Cargando…

Insights into the biosynthesis of septacidin l-heptosamine moiety unveils a VOC family sugar epimerase

l-Heptopyranoses are important components of bacterial polysaccharides and biological active secondary metabolites like septacidin (SEP), which represents a group of nucleoside antibiotics with antitumor, antifungal, and pain-relief activities. However, little is known about the formation mechanisms...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chen, Meng, Guo, Zhengyan, Sun, Jinyuan, Tang, Wei, Wang, Min, Tang, Yue, Li, Pengwei, Wu, Bian, Chen, Yihua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9978623/ https://www.ncbi.nlm.nih.gov/pubmed/36873169 http://dx.doi.org/10.1016/j.apsb.2022.05.031

Ejemplares similares

Spinning sugars in antigen biosynthesis: characterization of the Coxiella burnetii and Streptomyces griseus TDP-sugar epimerases
por: Cross, Alice R., et al.
Publicado: (2022)

A Rice Plastidial Nucleotide Sugar Epimerase Is Involved in Galactolipid Biosynthesis and Improves Photosynthetic Efficiency
por: Li, Chunlai, et al.
Publicado: (2011)

Initiating polyketide biosynthesis by on-line methyl esterification
por: Li, Pengwei, et al.
Publicado: (2021)

Converting Galactose into the Rare Sugar Talose with Cellobiose 2-Epimerase as Biocatalyst
por: Van Overtveldt, Stevie, et al.
Publicado: (2018)

Biosynthetic access to the rare antiarose sugar via an unusual reductase-epimerase
por: Yan, Yijun, et al.
Publicado: (2020)

Activation of three natural product biosynthetic gene clusters from Streptomyces lavendulae CGMCC 4.1386 by a reporter-guided strategy
por: Li, Pengwei, et al.
Publicado: (2018)

Transcriptome Analysis Unveiled the Intricate Interplay between Sugar Metabolism and Lipid Biosynthesis in Symplocos paniculate Fruit
por: Li, Wenjun, et al.
Publicado: (2023)

Conformation-dependent restraints for polynucleotides: the sugar moiety
por: Kowiel, Marcin, et al.
Publicado: (2020)

Mechanism and inhibition of human UDP-GlcNAc 2-epimerase, the key enzyme in sialic acid biosynthesis
por: Chen, Sheng-Chia, et al.
Publicado: (2016)

Identification of the UDP-glucose-4-epimerase required for galactofuranose biosynthesis and galactose metabolism in A. niger
por: Park, Joohae, et al.
Publicado: (2014)

Crystal structure of a UDP-GlcNAc epimerase for surface polysaccharide biosynthesis in Acinetobacter baumannii
por: Shah, Bhumika S., et al.
Publicado: (2018)

Impact of xylose epimerase on sugar assimilation and sensing in recombinant Saccharomyces cerevisiae carrying different xylose-utilization pathways
por: Persson, Viktor C., et al.
Publicado: (2023)

Origin of the 3-methylglutaryl moiety in caprazamycin biosynthesis
por: Bär, Daniel, et al.
Publicado: (2022)

Structural basis for redox sensitivity in Corynebacterium glutamicum diaminopimelate epimerase: an enzyme involved in l-lysine biosynthesis
por: Sagong, Hye-Young, et al.
Publicado: (2017)

Two tomato GDP-D-mannose epimerase isoforms involved in ascorbate biosynthesis play specific roles in cell wall biosynthesis and development
por: Mounet-Gilbert, Louise, et al.
Publicado: (2016)

Integrating Metabolomics and Transcriptomics to Unveil Atisine Biosynthesis in Aconitum gymnandrum Maxim
por: Chen, Lingli, et al.
Publicado: (2022)

Structural analysis of a bacterial UDP-sugar 2-epimerase reveals the active site architecture before and after catalysis
por: Thoden, James B., et al.
Publicado: (2023)

Molecular Evolution of GDP-D-Mannose Epimerase (GME), a Key Gene in Plant Ascorbic Acid Biosynthesis
por: Tao, Junjie, et al.
Publicado: (2018)

Insights into spatial configuration of a galactosylated epitope required to trigger arthritogenic T-cell receptors specific for the sugar moiety
por: Glatigny, Simon, et al.
Publicado: (2007)

The origin and biosynthesis of the naphthalenoid moiety of juglone in black walnut
por: McCoy, Rachel M., et al.
Publicado: (2018)

Construction of an Alternative NAD(+) De Novo Biosynthesis Pathway
por: Ding, Yong, et al.
Publicado: (2021)

The Engineering, Expression, and Immobilization of Epimerases for D-allulose Production
por: Tan, Jin Hao, et al.
Publicado: (2023)

N-acetylmannosamine-6-phosphate 2-epimerase uses a novel substrate-assisted mechanism to catalyze amino sugar epimerization
por: Currie, Michael J., et al.
Publicado: (2021)

Expanding the Enzyme Repertoire for Sugar Nucleotide Epimerization: the CDP-Tyvelose 2-Epimerase from Thermodesulfatator atlanticus for Glucose/Mannose Interconversion
por: Rapp, Christian, et al.
Publicado: (2021)

Production of Glycopeptide Derivatives for Exploring Substrate Specificity of Human OGA Toward Sugar Moiety
por: Li, Shanshan, et al.
Publicado: (2019)

Midecamycin Is Inactivated by Several Different Sugar Moieties at Its Inactivation Site
por: Lin, Ru, et al.
Publicado: (2021)

KasQ an Epimerase Primes the Biosynthesis of Aminoglycoside Antibiotic Kasugamycin and KasF/H Acetyltransferases Inactivate Its Activity
por: Rattinam, Rajesh, et al.
Publicado: (2022)

Full-length transcriptome and metabolite analysis reveal reticuline epimerase-independent pathways for benzylisoquinoline alkaloids biosynthesis in Sinomenium acutum
por: Yang, Yufan, et al.
Publicado: (2022)

A Mutation of a Putative NDP-Sugar Epimerase Gene in Ralstonia pseudosolanacearum Attenuates Exopolysaccharide Production and Bacterial Virulence in Tomato Plant
por: Lee, Hyoung Ju, et al.
Publicado: (2023)

Mechanistic characterization of UDP‐glucuronic acid 4‐epimerase
por: Borg, Annika J. E., et al.
Publicado: (2020)

Unveiling the Molecular Basis of Mascarpone Cheese Aroma: VOCs analysis by SPME-GC/MS and PTR-ToF-MS
por: Capozzi, Vittorio, et al.
Publicado: (2020)

Insect growth regulators with hydrazide moiety inhibit strigolactone biosynthesis in rice
por: Kawada, Kojiro, et al.
Publicado: (2022)

Targeting N-Glycan Cryptic Sugar Moieties for Broad-Spectrum Virus Neutralization: Progress in Identifying Conserved Molecular Targets in Viruses of Distinct Phylogenetic Origins
por: Wang, Denong, et al.
Publicado: (2015)

Methylmalonyl-CoA Epimerase Deficiency Mimicking Propionic Aciduria
por: Abily-Donval, Lenaig, et al.
Publicado: (2017)

Uncovering a superfamily of nickel-dependent hydroxyacid racemases and epimerases
por: Desguin, Benoît, et al.
Publicado: (2020)

Exploiting Mannuronan C-5 Epimerases in Commercial Alginate Production
por: Tøndervik, Anne, et al.
Publicado: (2020)

Galactose epimerase deficiency: lessons from the GalNet registry
por: Derks, Britt, et al.
Publicado: (2022)

Fragranced Products and VOCs
por: Singal, Madhuri, et al.
Publicado: (2011)

Expanding structural diversity of 5′-aminouridine moiety of sansanmycin via mutational biosynthesis
por: Lu, Yuan, et al.
Publicado: (2023)

One-pot biosynthesis of N-acetylneuraminic acid from chitin via combination of chitin-degrading enzymes, N-acetylglucosamine-2-epimerase, and N-neuraminic acid aldolase
por: Liu, Quanzhen, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_4d6fvm3s6bsiv8klfiu33hq149