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Structural investigation of Ayurveda Lauha (Iron) Bhasma

In Ayurveda, ‘Lauha’ (Iron) Bhasma is primarily used to cure diseases related to iron deficiency in humans. It is produced from purified raw metallic iron using a combination of multi-step traditional preparation processes described in the Ayurveda literature. Here, we present the results of structu...

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Autores principales: Tiwari, M.K., Singh, Arjun, Khooha, Ajay, Goutam, U.K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9978626/
https://www.ncbi.nlm.nih.gov/pubmed/36822148
http://dx.doi.org/10.1016/j.jaim.2023.100690
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author Tiwari, M.K.
Singh, Arjun
Khooha, Ajay
Goutam, U.K.
author_facet Tiwari, M.K.
Singh, Arjun
Khooha, Ajay
Goutam, U.K.
author_sort Tiwari, M.K.
collection PubMed
description In Ayurveda, ‘Lauha’ (Iron) Bhasma is primarily used to cure diseases related to iron deficiency in humans. It is produced from purified raw metallic iron using a combination of multi-step traditional preparation processes described in the Ayurveda literature. Here, we present the results of structural investigation performed on the medicinal grade ‘Lauha’ Bhasma using various X-ray based techniques. Our results indicate that after several rounds of heating and cooling in specific conditions following the Ayurvedic preparation procedure, metallic iron eventually converts to a natural iron-oxide mineral belonging to the magnetite group. Scanning electron microscopy (SEM) and X-ray standing wave assisted fluorescence measurements carried out on powdered Bhasma specimen reveal that the magnetite micro-particles in the Bhasma specimen are usually present in the form of agglomerates of nano-particles. We anticipate that the Ayurvedic Lauha Bhasma has great potential for noninvasive localized target killing of cancer cells, particularly in sensitive parts of the human body such as the brain, spinal cord, and lungs, via necrosis by application of an alternating external magnetic field or photo electron generation through X-rays.
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spelling pubmed-99786262023-03-03 Structural investigation of Ayurveda Lauha (Iron) Bhasma Tiwari, M.K. Singh, Arjun Khooha, Ajay Goutam, U.K. J Ayurveda Integr Med Original Research Article In Ayurveda, ‘Lauha’ (Iron) Bhasma is primarily used to cure diseases related to iron deficiency in humans. It is produced from purified raw metallic iron using a combination of multi-step traditional preparation processes described in the Ayurveda literature. Here, we present the results of structural investigation performed on the medicinal grade ‘Lauha’ Bhasma using various X-ray based techniques. Our results indicate that after several rounds of heating and cooling in specific conditions following the Ayurvedic preparation procedure, metallic iron eventually converts to a natural iron-oxide mineral belonging to the magnetite group. Scanning electron microscopy (SEM) and X-ray standing wave assisted fluorescence measurements carried out on powdered Bhasma specimen reveal that the magnetite micro-particles in the Bhasma specimen are usually present in the form of agglomerates of nano-particles. We anticipate that the Ayurvedic Lauha Bhasma has great potential for noninvasive localized target killing of cancer cells, particularly in sensitive parts of the human body such as the brain, spinal cord, and lungs, via necrosis by application of an alternating external magnetic field or photo electron generation through X-rays. Elsevier 2023 2023-02-21 /pmc/articles/PMC9978626/ /pubmed/36822148 http://dx.doi.org/10.1016/j.jaim.2023.100690 Text en © 2023 The Authors https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Original Research Article
Tiwari, M.K.
Singh, Arjun
Khooha, Ajay
Goutam, U.K.
Structural investigation of Ayurveda Lauha (Iron) Bhasma
title Structural investigation of Ayurveda Lauha (Iron) Bhasma
title_full Structural investigation of Ayurveda Lauha (Iron) Bhasma
title_fullStr Structural investigation of Ayurveda Lauha (Iron) Bhasma
title_full_unstemmed Structural investigation of Ayurveda Lauha (Iron) Bhasma
title_short Structural investigation of Ayurveda Lauha (Iron) Bhasma
title_sort structural investigation of ayurveda lauha (iron) bhasma
topic Original Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9978626/
https://www.ncbi.nlm.nih.gov/pubmed/36822148
http://dx.doi.org/10.1016/j.jaim.2023.100690
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