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Measuring multimorbidity in research: Delphi consensus study

OBJECTIVE: To develop international consensus on the definition and measurement of multimorbidity in research. DESIGN: Delphi consensus study. SETTING: International consensus; data collected in three online rounds from participants between 30 November 2020 and 18 May 2021. PARTICIPANTS: Professiona...

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Autores principales: Ho, Iris S S, Azcoaga-Lorenzo, Amaya, Akbari, Ashley, Davies, Jim, Khunti, Kamlesh, Kadam, Umesh T, Lyons, Ronan A, McCowan, Colin, Mercer, Stewart W, Nirantharakumar, Krishnarajah, Staniszewska, Sophie, Guthrie, Bruce
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9978673/
https://www.ncbi.nlm.nih.gov/pubmed/36936594
http://dx.doi.org/10.1136/bmjmed-2022-000247
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author Ho, Iris S S
Azcoaga-Lorenzo, Amaya
Akbari, Ashley
Davies, Jim
Khunti, Kamlesh
Kadam, Umesh T
Lyons, Ronan A
McCowan, Colin
Mercer, Stewart W
Nirantharakumar, Krishnarajah
Staniszewska, Sophie
Guthrie, Bruce
author_facet Ho, Iris S S
Azcoaga-Lorenzo, Amaya
Akbari, Ashley
Davies, Jim
Khunti, Kamlesh
Kadam, Umesh T
Lyons, Ronan A
McCowan, Colin
Mercer, Stewart W
Nirantharakumar, Krishnarajah
Staniszewska, Sophie
Guthrie, Bruce
author_sort Ho, Iris S S
collection PubMed
description OBJECTIVE: To develop international consensus on the definition and measurement of multimorbidity in research. DESIGN: Delphi consensus study. SETTING: International consensus; data collected in three online rounds from participants between 30 November 2020 and 18 May 2021. PARTICIPANTS: Professionals interested in multimorbidity and people with long term conditions were recruited to professional and public panels. RESULTS: 150 professional and 25 public participants completed the first survey round. Response rates for rounds 2/3 were 83%/92% for professionals and 88%/93% in the public panel, respectively. Across both panels, the consensus was that multimorbidity should be defined as two or more long term conditions. Complex multimorbidity was perceived to be a useful concept, but the panels were unable to agree on how to define it. Both panels agreed that conditions should be included in a multimorbidity measure if they were one or more of the following: currently active; permanent in their effects; requiring current treatment, care, or therapy; requiring surveillance; or relapsing-remitting conditions requiring ongoing care. Consensus was reached for 24 conditions to always include in multimorbidity measures, and 35 conditions to usually include unless a good reason not to existed. Simple counts were preferred for estimating prevalence and examining clustering or trajectories, and weighted measures were preferred for risk adjustment and outcome prediction. CONCLUSIONS: Previous multimorbidity research is limited by inconsistent definitions and approaches to measuring multimorbidity. This Delphi study identifies professional and public panel consensus guidance to facilitate consistency of definition and measurement, and to improve study comparability and reproducibility.
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spelling pubmed-99786732023-03-16 Measuring multimorbidity in research: Delphi consensus study Ho, Iris S S Azcoaga-Lorenzo, Amaya Akbari, Ashley Davies, Jim Khunti, Kamlesh Kadam, Umesh T Lyons, Ronan A McCowan, Colin Mercer, Stewart W Nirantharakumar, Krishnarajah Staniszewska, Sophie Guthrie, Bruce BMJ Med Research OBJECTIVE: To develop international consensus on the definition and measurement of multimorbidity in research. DESIGN: Delphi consensus study. SETTING: International consensus; data collected in three online rounds from participants between 30 November 2020 and 18 May 2021. PARTICIPANTS: Professionals interested in multimorbidity and people with long term conditions were recruited to professional and public panels. RESULTS: 150 professional and 25 public participants completed the first survey round. Response rates for rounds 2/3 were 83%/92% for professionals and 88%/93% in the public panel, respectively. Across both panels, the consensus was that multimorbidity should be defined as two or more long term conditions. Complex multimorbidity was perceived to be a useful concept, but the panels were unable to agree on how to define it. Both panels agreed that conditions should be included in a multimorbidity measure if they were one or more of the following: currently active; permanent in their effects; requiring current treatment, care, or therapy; requiring surveillance; or relapsing-remitting conditions requiring ongoing care. Consensus was reached for 24 conditions to always include in multimorbidity measures, and 35 conditions to usually include unless a good reason not to existed. Simple counts were preferred for estimating prevalence and examining clustering or trajectories, and weighted measures were preferred for risk adjustment and outcome prediction. CONCLUSIONS: Previous multimorbidity research is limited by inconsistent definitions and approaches to measuring multimorbidity. This Delphi study identifies professional and public panel consensus guidance to facilitate consistency of definition and measurement, and to improve study comparability and reproducibility. BMJ Publishing Group 2022-07-27 /pmc/articles/PMC9978673/ /pubmed/36936594 http://dx.doi.org/10.1136/bmjmed-2022-000247 Text en © Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY. Published by BMJ. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution 4.0 Unported (CC BY 4.0) license, which permits others to copy, redistribute, remix, transform and build upon this work for any purpose, provided the original work is properly cited, a link to the licence is given, and indication of whether changes were made. See: https://creativecommons.org/licenses/by/4.0/.
spellingShingle Research
Ho, Iris S S
Azcoaga-Lorenzo, Amaya
Akbari, Ashley
Davies, Jim
Khunti, Kamlesh
Kadam, Umesh T
Lyons, Ronan A
McCowan, Colin
Mercer, Stewart W
Nirantharakumar, Krishnarajah
Staniszewska, Sophie
Guthrie, Bruce
Measuring multimorbidity in research: Delphi consensus study
title Measuring multimorbidity in research: Delphi consensus study
title_full Measuring multimorbidity in research: Delphi consensus study
title_fullStr Measuring multimorbidity in research: Delphi consensus study
title_full_unstemmed Measuring multimorbidity in research: Delphi consensus study
title_short Measuring multimorbidity in research: Delphi consensus study
title_sort measuring multimorbidity in research: delphi consensus study
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9978673/
https://www.ncbi.nlm.nih.gov/pubmed/36936594
http://dx.doi.org/10.1136/bmjmed-2022-000247
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