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Establishment of a core outcome set for burn care research: development and international consensus
OBJECTIVE: To develop a core outcome set for international burn research. DESIGN: Development and international consensus, from April 2017 to November 2019. METHODS: Candidate outcomes were identified from systematic reviews and stakeholder interviews. Through a Delphi survey, international clinicia...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9978679/ https://www.ncbi.nlm.nih.gov/pubmed/36936572 http://dx.doi.org/10.1136/bmjmed-2022-000183 |
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author | Young, Amber Davies, Anna Tsang, Carmen Kirkham, Jamie Potokar, Tom Gibran, Nicole Tyack, Zephanie Meirte, Jill Harada, Teruichi Dheansa, Baljit Dumville, Jo Metcalfe, Chris Ahuja, Rajeev Wood, Fiona Gaskell, Sarah Brookes, Sara Smailes, Sarah Jeschke, Marc Cinar, Murat Ali Zia, Nukhba Moghazy, Amr Mathers, Jonathan Falder, Sian Edgar, Dale Blazeby, Jane Mary |
author_facet | Young, Amber Davies, Anna Tsang, Carmen Kirkham, Jamie Potokar, Tom Gibran, Nicole Tyack, Zephanie Meirte, Jill Harada, Teruichi Dheansa, Baljit Dumville, Jo Metcalfe, Chris Ahuja, Rajeev Wood, Fiona Gaskell, Sarah Brookes, Sara Smailes, Sarah Jeschke, Marc Cinar, Murat Ali Zia, Nukhba Moghazy, Amr Mathers, Jonathan Falder, Sian Edgar, Dale Blazeby, Jane Mary |
author_sort | Young, Amber |
collection | PubMed |
description | OBJECTIVE: To develop a core outcome set for international burn research. DESIGN: Development and international consensus, from April 2017 to November 2019. METHODS: Candidate outcomes were identified from systematic reviews and stakeholder interviews. Through a Delphi survey, international clinicians, researchers, and UK patients prioritised outcomes. Anonymised feedback aimed to achieve consensus. Pre-defined criteria for retaining outcomes were agreed. A consensus meeting with voting was held to finalise the core outcome set. RESULTS: Data source examination identified 1021 unique outcomes grouped into 88 candidate outcomes. Stakeholders in round 1 of the survey, included 668 health professionals from 77 countries (18% from low or low middle income countries) and 126 UK patients or carers. After round 1, one outcome was discarded, and 13 new outcomes added. After round 2, 69 items were discarded, leaving 31 outcomes for the consensus meeting. Outcome merging and voting, in two rounds, with prespecified thresholds agreed seven core outcomes: death, specified complications, ability to do daily tasks, wound healing, neuropathic pain and itch, psychological wellbeing, and return to school or work. CONCLUSIONS: This core outcome set caters for global burn research, and future trials are recommended to include measures of these outcomes. |
format | Online Article Text |
id | pubmed-9978679 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | BMJ Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-99786792023-03-16 Establishment of a core outcome set for burn care research: development and international consensus Young, Amber Davies, Anna Tsang, Carmen Kirkham, Jamie Potokar, Tom Gibran, Nicole Tyack, Zephanie Meirte, Jill Harada, Teruichi Dheansa, Baljit Dumville, Jo Metcalfe, Chris Ahuja, Rajeev Wood, Fiona Gaskell, Sarah Brookes, Sara Smailes, Sarah Jeschke, Marc Cinar, Murat Ali Zia, Nukhba Moghazy, Amr Mathers, Jonathan Falder, Sian Edgar, Dale Blazeby, Jane Mary BMJ Med Research OBJECTIVE: To develop a core outcome set for international burn research. DESIGN: Development and international consensus, from April 2017 to November 2019. METHODS: Candidate outcomes were identified from systematic reviews and stakeholder interviews. Through a Delphi survey, international clinicians, researchers, and UK patients prioritised outcomes. Anonymised feedback aimed to achieve consensus. Pre-defined criteria for retaining outcomes were agreed. A consensus meeting with voting was held to finalise the core outcome set. RESULTS: Data source examination identified 1021 unique outcomes grouped into 88 candidate outcomes. Stakeholders in round 1 of the survey, included 668 health professionals from 77 countries (18% from low or low middle income countries) and 126 UK patients or carers. After round 1, one outcome was discarded, and 13 new outcomes added. After round 2, 69 items were discarded, leaving 31 outcomes for the consensus meeting. Outcome merging and voting, in two rounds, with prespecified thresholds agreed seven core outcomes: death, specified complications, ability to do daily tasks, wound healing, neuropathic pain and itch, psychological wellbeing, and return to school or work. CONCLUSIONS: This core outcome set caters for global burn research, and future trials are recommended to include measures of these outcomes. BMJ Publishing Group 2022-07-07 /pmc/articles/PMC9978679/ /pubmed/36936572 http://dx.doi.org/10.1136/bmjmed-2022-000183 Text en © Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY. Published by BMJ. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution 4.0 Unported (CC BY 4.0) license, which permits others to copy, redistribute, remix, transform and build upon this work for any purpose, provided the original work is properly cited, a link to the licence is given, and indication of whether changes were made. See: https://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Research Young, Amber Davies, Anna Tsang, Carmen Kirkham, Jamie Potokar, Tom Gibran, Nicole Tyack, Zephanie Meirte, Jill Harada, Teruichi Dheansa, Baljit Dumville, Jo Metcalfe, Chris Ahuja, Rajeev Wood, Fiona Gaskell, Sarah Brookes, Sara Smailes, Sarah Jeschke, Marc Cinar, Murat Ali Zia, Nukhba Moghazy, Amr Mathers, Jonathan Falder, Sian Edgar, Dale Blazeby, Jane Mary Establishment of a core outcome set for burn care research: development and international consensus |
title | Establishment of a core outcome set for burn care research: development and international consensus |
title_full | Establishment of a core outcome set for burn care research: development and international consensus |
title_fullStr | Establishment of a core outcome set for burn care research: development and international consensus |
title_full_unstemmed | Establishment of a core outcome set for burn care research: development and international consensus |
title_short | Establishment of a core outcome set for burn care research: development and international consensus |
title_sort | establishment of a core outcome set for burn care research: development and international consensus |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9978679/ https://www.ncbi.nlm.nih.gov/pubmed/36936572 http://dx.doi.org/10.1136/bmjmed-2022-000183 |
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